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Additionally, the concentration of AOD9604 in the synovial fluid after injection was estimated to be about 0.19 mg/mL, similar to concentrations used in previous GH injection studies in animal models

theoretical risks include increased hypoglycaemia, unpredictable cardiovascular effects, and compounded uncertainty from two incompletely characterised compounds

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observed in Nature Medicine , NNMT inhibition in adipose tissue produced favorable body composition changes without negatively impacting muscle mass (Kraus et al., Nature Medicine )

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